A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

François Pierre J. Martin, Marc Emmanuel Dumas, Yulan Wang, Cristina Legido-Quigley, Ivan K.S. Yap, Huiru Tang, Séverine Zirah, Gerard M. Murphy, Olivier Cloarec, John C. Lindon, Norbert Sprenger, Laurent B. Fay, Sunil Kochhar, Peter Van Bladeren, Elaine Holmes, Jeremy K. Nicholson^*