Sub-2μm porous silica materials for enhanced separation performance in liquid chromatography

Yong Wang, Feng Ai, Siu Choon Ng, Timothy Thatt Yang Tan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

63 Citations (Scopus)

Abstract

Fully or partially sub-2 μm porous silica materials have garnered strong interests as column packing materials in separation and analytical technologies due to the promise of rapid separation, enhanced efficiency and separation resolution. Silica support materials of different morphology and sub-2 μm size have been developed to improve separation performances in liquid chromatography (LC) and capillary electrochromatography (CEC). The current review highlights the recent development of sub-2 μm fully/partially porous silica materials and the demonstrations of their enhanced performance in achiral and chiral chromatography.

Original languageEnglish
Pages (from-to)99-109
Number of pages11
JournalJournal of Chromatography A
Volume1228
DOIs
Publication statusPublished - Mar 9 2012
Externally publishedYes

ASJC Scopus Subject Areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Keywords

  • Achiral separation
  • Capillary electrochromatography
  • Enantioselective separation
  • High efficiency
  • Sub-2μm porous silica material
  • Ultra-high performance liquid chromatography

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