Dr Andrea Nanetti received his university education in Historical Sciences between 1986 and 2000 in Italy (University of Bologna), France (University of Paris 1 Panthéon-Sorbonne and Paris 10 Nanterre), Germany (University of Cologne), Greece (National Hellenic Research Foundation), and USA (Brown University), where he has been instructed by world's leading professors to work on research questions and solutions through the cross-fertilization of different methodologies (historical, philological, diplomatic, aesthetic, anthropological, and computational). He pioneered digital humanities projects for archival documents (1997-1999 State Archive in Venice and 2005-2010 State Archive in Ravenna), chronicles (2002-2004 Virtual Library of Venetian Chronicles), historical maps (2000, Imola from Leonardo da Vinci to today), and pre-modern historical primary sources (2007-today, cloud platform for Afro-Eurasia). His academic research has been supported by his entrepreneurial experience, which started in 2001, when he was awarded a prize in the “StartCup” of the University of Bologna and the General Confederation of the Italian Industry (the first Italian business plan competition devoted to projects with high content of knowledge) to establish Meduproject Pte Ltd. In 2002 the company was founded as a spin off of the University of Bologna focused on projects at the interface of cultural heritage and S&T: access to heritage, networking of conservation-restoration experts, and support to heritage management (advisor to public and private institutions in strategic decisions). Since 2008 the company manages and supports the web platforms of Andrea Nanetti's main research project called Engineering Historical Memory (EHM), which thrives on meeting the next challenge in developing and testing old and new sets of shared conceptualizations and formal specifications for heritage data management systems. The presentation of the results of the project was awarded best conference paper at 2013 Culture and Computing (Kyoto, Japan), and has been funded, among others, by Microsoft Research (2014-2017). Since 1996, he has published 20 multilingual books (13 single authored, present in distinguished libraries around the world), 2 edited journals, and over 70 essays in scientific journals and books in English, Italian, Chinese, Spanish and Modern Greek on intercontinental trade-conflict-diplomacy relationships (Afro-Eurasia ca. 1100-1500), national art-heritage-politics relationships (Italy, Greece, and China 19th-20th centuries), territorial man-heritage-landscape systems (Imola 403-1789, and Venetian Messenia 1209-1500 & 1684-1718), and, more recently, cultural and biological heritage systems in human interpretation of the external world (seen as artificial intelligence amplification ante litteram). Dr Nanetti is currently playing multiple editorial roles including the ‘Committee for the Publication of the Sources for the History of Venice’ since 2000. He was the Founding Co-Chair of the Singapore Heritage Science Conference series (2014-) and a member of numerous Conference Committees including the ‘International Conference on Culture and Computing’, VSMM, SOTICS, and CCS. Dr Nanetti lives with his family in Singapore, in the Nanyang Technological University campus, where he serves as Tenured Associate Professor and Associate Chair (Research) at the School of Art, Design and Media, as Senior Researcher in the Complexity Institute, with a courtesy appointment at the School of Humanities. At NTU he is also a Faculty Member of the University Scholarly Programme and of the MSc in Technopreneurship and Innovation Programme. Internationally he serves the domain of heritage science as Founding Co-Director (International Relations) of the International Research Centre for Architectural Heritage Conservation at Shanghai Jiao Tong University, and as Founding Member of the Board of Directors of the Maniatakeion Foundation (Athens, Greece).