Miao Yansong

Research areas and projects: Miao Lab research mainly focuses on studying the mechanisms of actin assembly in polarized fungal growth and plant immunity. Miao Lab interested in how diverse extracellular and intracellular signals regulate actin assembly underlying diverse physiological and pathological processes in eukaryotic cells. Actin filament assembly contributes to the multiple cellular pathways pleiotropically, by its dynamic assembly and disassembly upon cellular needs and specific stimuli, such as the activation of polarized cell growth or the host immune responses during defense mechanisms against pathogenic attack. In the much crowd intracellular environment, actin-binding proteins (ABPs) precisely regulate the dynamics assembly and re-organization of actin networks, in cooperative and competitive manners. We are particularly interested in how the intrinsically disordered regions (IDRs) of ABPs perceive the signals to trigger re-organization of actin assembly, by regulating the protein dynamics, protein conformation, and protein-protein interactions, via interdisciplinary approaches, such as biochemical assay, advanced cell imaging, genetic approaches. Teaching: BS1100, BS4002, BS7001 Honours and Awards: • Human Frontier Science Program Postdoc Long-term Fellow (2010-2013), University of California, Berkeley, CA, USA • Nanyang Assistant Professorship (NAP), Nanyang Technological University, Singapore Qualification: • Assistant Professor (2015-present), School of Biological Science, NTU, Singapore • Postdoctoral Fellow (2010-2014), University of California, Berkeley, CA, USA • Ph.D. (2006-2009), The Chinese University of Hong Kong, Hong Kong • Mphil (2004-2006), The Chinese University of Hong Kong, Hong Kong • Bsc (1998-2002), Zhejiang University, Hangzhou, China