Personal profile
Biography
ACADEMIC QUALIFICATIONS:
• University of Hannover, PhD, Faculty of Chemistry, 2002, Molecular analysis of IL-6/gp130 dependent signal transduction pathways during liver regeneration (Research work was done in the Department of Gastroenterology, Hepatology & Endocrinology, Medical School Hannover, Hannover, Germany)
• University of Hannover, Master of Science, Faculty of Biology, 1998, Molecular biological characterization of the ´fasciata´-syndrom of the pea (Pisum Sativum)
POSITION & HONORARY APPOINTMENTS:
• 2023-present: Assoc/Prof. of Molecular Metabolism, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
• 2015-present: Group Leader, Genome Institute of Singapore, Laboratory of In Vivo Genetics and Gene Therapy, Singapore
• 2019-present: Adjunct Prof. Nanyang Technological University, School of Biological Sciences
• 2020-present: Scientific Co-Founder and Scientific Advisor, LERNA Biopharma (formerly known as Cargene Therapeutics), Singapore
PATENTS:
Zender, L, Wüstefeld, T, WO2012136859: Medicament for liver regeneration and for treatment of liver failure.
Iakovleva, V., Wuestefeld, T. WO2022025827: Method of stimulating proliferation of a cell.
Hora, S., Kaur, A. Wuestefeld, T. SG patent application no.: 10202301535X: Enhancing liver regeneration and counteracting liver disease.
Potapova, A., Wuestefeld, T.: SG patent application no.: 10202302421T: GENE SIGNATURES FOR LIVER DISEASE AND USES THERE OF.
SIGNIFICANT AWARDS:
2021 Public Sector Transformation (PST) Awards – One Public Service Award, in recognition of contributions to Building Capacity & Capability for COVID-19 Testing
2021 Firefly Award-Borderless Award (Gold) in recognition of contributions to the Stronghold Diagnostic Lab (SDL) in Singapore
2020 Cargen Therapeutics co –founded by T. Wuestefeld got the Golden Ticket awarded by Novo Nordisk and LabCentral
2004-05 2 year scholarship of the DFG (DFG-Project WU 373/1-1)
1999-2001 Scholarship of the DFG, Graduiertenkolleg (GRK 139/3-00) “Molecular Pathophysiology of the cell growth”
1995-1996 Scholarship of the German Academic Exchange Program (DAAD) for studying at Northeastern University, Boston, USA
RESEARCH INTERESTS:
Liver Disease Modelling, NAFLD, Metabolic syndrome, Aging, Senescence, Liver Cancer, Gene Therapy, Nucleic Acid Therapeutics, In Vivo Functional Genetic Screens, Translational Research
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):