多排螺旋CT结合碘克沙醇对图像质量及肾功能的影响

This paper discussed the effect of multi-slice spiral CT combined with isotonic contrast agent iodixanol on image quality and renal function was discussed. 110 coronary heart disease patients underwent multi-slice spiral CT were selected, and divided them into observation group (n=60) and control group (n=50) according to different contrast media, both groups were given multi-slice spiral CT examination. The observation group was given isosmotic contrast agent iodixanol, and the control group was given iohexol, the image quality and renal function of the two groups were analyzed. There was no significant difference in the subjective evaluation results of image quality between the observation group and the control group (P>0.05). There were no significant differences in CT values, noise value (SD), signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of ascending aortic root, left main artery and right coronary artery between observation group and control group (P>0.05). The serum creatinine (Scr) and blood urea nitrogen (BUN) after angiography in observation group were significantly lower than those in control group (P<0.05). The incidence of adverse reactions in observation group was 1.67%, which was significantly lower than that in control group (P<0.05). Multi slice spiral CT combined with isotonic contrast agent iodixanol has high application value, good image quality and no significant effect on renal function.