TY - JOUR
T1 - A comparative study of diagnostic scoring systems for autoimmune pancreatitis
AU - Van Heerde, Marianne J.
AU - Buijs, Jorie
AU - Rauws, Erik A.
AU - De Buy Wenniger, Lucas J.Maillette
AU - Hansen, Bettina E.
AU - Biermann, Katharina
AU - Verheij, Joanne
AU - Vleggaar, Frank P.
AU - Brink, Menno A.
AU - Beuers, Ulrich H.W.
AU - Kuipers, Ernst J.
AU - Van Buuren, Henk R.
AU - Bruno, Marco J.
PY - 2014/5
Y1 - 2014/5
N2 - OBJECTIVE: Several diagnostic scoring systems for autoimmune pancreatitis (AIP) have been proposed including the Asian, HISORt (Histology, Imaging, Serology, Other organ involvement and Response to therapy), and International Consensus Diagnostic Criteria (ICDC), which have been compared by a few studies. We evaluated the diagnostic performance of these criteria in patients diagnosed with AIP between May 1992 and August 2011. METHODS: Scoring systems were applied retrospectively using data obtained in the initial evaluation period, before pancreatic resection was performed. RESULTS: One hundred fourteen cases with AIP were included. Eighty-two percent met the diagnostic criteria for AIP according to either the Asian, HISORt, or ICDC criteria. Only 33% met the Asian criteria, probably mainly related to a low rate of diagnostic pancreatography. In 18%, all scoring systems failed to confirm the diagnosis, even though these patients were considered to have a firm diagnosis of AIP. CONCLUSIONS: In this cohort of AIP patients, the 3 major diagnostic scoring systems for AIP proved to be complementary rather than overlapping. Our data indicate that one-fifth of our AIP patients do not meet any of these scoring systems. The ICDC, Asian, and HISORt criteria should be considered as useful clinical tools but not as criterion standard for the diagnosis.
AB - OBJECTIVE: Several diagnostic scoring systems for autoimmune pancreatitis (AIP) have been proposed including the Asian, HISORt (Histology, Imaging, Serology, Other organ involvement and Response to therapy), and International Consensus Diagnostic Criteria (ICDC), which have been compared by a few studies. We evaluated the diagnostic performance of these criteria in patients diagnosed with AIP between May 1992 and August 2011. METHODS: Scoring systems were applied retrospectively using data obtained in the initial evaluation period, before pancreatic resection was performed. RESULTS: One hundred fourteen cases with AIP were included. Eighty-two percent met the diagnostic criteria for AIP according to either the Asian, HISORt, or ICDC criteria. Only 33% met the Asian criteria, probably mainly related to a low rate of diagnostic pancreatography. In 18%, all scoring systems failed to confirm the diagnosis, even though these patients were considered to have a firm diagnosis of AIP. CONCLUSIONS: In this cohort of AIP patients, the 3 major diagnostic scoring systems for AIP proved to be complementary rather than overlapping. Our data indicate that one-fifth of our AIP patients do not meet any of these scoring systems. The ICDC, Asian, and HISORt criteria should be considered as useful clinical tools but not as criterion standard for the diagnosis.
KW - Autoimmune pancreatitis
KW - Diagnostic criteria
KW - IgG4
KW - IgG4-related disease
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U2 - 10.1097/MPA.0000000000000045
DO - 10.1097/MPA.0000000000000045
M3 - Article
C2 - 24658319
AN - SCOPUS:84898468574
SN - 0885-3177
VL - 43
SP - 559
EP - 564
JO - Pancreas
JF - Pancreas
IS - 4
ER -
