A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: Synthesis of 4-bromoisoquinolones

Pei Chui Too; Shunsuke Chiba

doi:10.1039/c2cc33426g

A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: Synthesis of 4-bromoisoquinolones

Pei Chui Too, Shunsuke Chiba^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

A method for synthesis of 4-bromoisoquinolones has been developed starting from 2-alkynylbenzaldehydes and primary amines mediated by CuBr under an O₂ atmosphere, where CuBr plays multiple roles to facilitate the present reactions.

Original language	English
Pages (from-to)	7634-7636
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	61
DOIs	https://doi.org/10.1039/c2cc33426g
Publication status	Published - Jul 4 2012
Externally published	Yes

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: Synthesis of 4-bromoisoquinolones",

abstract = "A method for synthesis of 4-bromoisoquinolones has been developed starting from 2-alkynylbenzaldehydes and primary amines mediated by CuBr under an O2 atmosphere, where CuBr plays multiple roles to facilitate the present reactions.",

author = "Too, {Pei Chui} and Shunsuke Chiba",

year = "2012",

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doi = "10.1039/c2cc33426g",

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T2 - Synthesis of 4-bromoisoquinolones

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AU - Chiba, Shunsuke

PY - 2012/7/4

Y1 - 2012/7/4

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AB - A method for synthesis of 4-bromoisoquinolones has been developed starting from 2-alkynylbenzaldehydes and primary amines mediated by CuBr under an O2 atmosphere, where CuBr plays multiple roles to facilitate the present reactions.

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A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: Synthesis of 4-bromoisoquinolones

Abstract

ASJC Scopus Subject Areas

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