Abstract
(Chemical Equation Presented) A formal synthesis of porantheridine and a synthesis of its C6-epimer have been completed, employing silver-catalyzed allene cyclization to form a common cis-isoxazolidine intermediate and related N-acyl iminium ion intermediates for side-chain introduction. The stereochemistry of this step can be controlled by choice of the N-protection method.
| Original language | English |
|---|---|
| Pages (from-to) | 9460-9465 |
| Number of pages | 6 |
| Journal | Journal of Organic Chemistry |
| Volume | 74 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - Dec 18 2009 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Organic Chemistry