A highly enantioselective allyl-transfer through suppression of epimerization

Cheng Hsia Angeline Lee; Teck Peng Loh

doi:10.1016/j.tetlet.2004.06.014

A highly enantioselective allyl-transfer through suppression of epimerization

Cheng Hsia Angeline Lee, Teck Peng Loh^*

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

A highly enantioselective allyl transfer method was successfully developed, producing terminal homoallylic alcohols in moderate to high yields. In all cases, reactions were carried out under mild acid conditions; reducing the reaction temperature suppressed racemization.

Original language	English
Pages (from-to)	5819-5822
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	30
DOIs	https://doi.org/10.1016/j.tetlet.2004.06.014
Publication status	Published - Jul 19 2004
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Allyl transfer
Camphor
Chiral auxiliaries
Enantioselectivities
Homoallylic alcohols

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10.1016/j.tetlet.2004.06.014

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title = "A highly enantioselective allyl-transfer through suppression of epimerization",

abstract = "A highly enantioselective allyl transfer method was successfully developed, producing terminal homoallylic alcohols in moderate to high yields. In all cases, reactions were carried out under mild acid conditions; reducing the reaction temperature suppressed racemization.",

keywords = "Allyl transfer, Camphor, Chiral auxiliaries, Enantioselectivities, Homoallylic alcohols",

author = "Lee, {Cheng Hsia Angeline} and Loh, {Teck Peng}",

year = "2004",

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T1 - A highly enantioselective allyl-transfer through suppression of epimerization

AU - Lee, Cheng Hsia Angeline

AU - Loh, Teck Peng

PY - 2004/7/19

Y1 - 2004/7/19

N2 - A highly enantioselective allyl transfer method was successfully developed, producing terminal homoallylic alcohols in moderate to high yields. In all cases, reactions were carried out under mild acid conditions; reducing the reaction temperature suppressed racemization.

AB - A highly enantioselective allyl transfer method was successfully developed, producing terminal homoallylic alcohols in moderate to high yields. In all cases, reactions were carried out under mild acid conditions; reducing the reaction temperature suppressed racemization.

KW - Allyl transfer

KW - Camphor

KW - Chiral auxiliaries

KW - Enantioselectivities

KW - Homoallylic alcohols

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DO - 10.1016/j.tetlet.2004.06.014

M3 - Article

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SN - 0040-4039

VL - 45

SP - 5819

EP - 5822

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 30

ER -

A highly enantioselective allyl-transfer through suppression of epimerization

Abstract

ASJC Scopus Subject Areas

Keywords

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