A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate

Mahdi Rasouli; O. K. Tan; L. L. Sun; B. W. Mao; L. H. Gan

doi:10.1007/978-3-540-92841-6_212

A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate

Mahdi Rasouli, O. K. Tan, L. L. Sun, B. W. Mao, L. H. Gan

Nanyang Technological University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

A novel signal amplification mechanism for impedimetric biosensors is proposed. The proposed mechanism is based on humidity sensing properties of BST composite film and eliminates the need for application of bioactive labels for signal enhancement in amplified impedimetric biosensors. It suggests a good alternative to conventional impedimetric biosensors by improving the detection limit without adding any extra complexity to the system. It is direct and label-free, and can be employed for detection of a wide range of analytes. The sensing capability of the system was exemplified for detection of anti-BSA protein and a low detection limit of 10 ng/ml was obtained.

Original language	English
Title of host publication	13th International Conference on Biomedical Engineering - ICBME 2008
Pages	863-866
Number of pages	4
DOIs	https://doi.org/10.1007/978-3-540-92841-6_212
Publication status	Published - 2009
Externally published	Yes
Event	13th International Conference on Biomedical Engineering, ICBME 2008 - , Singapore Duration: Dec 3 2008 → Dec 6 2008

Publication series

Name	IFMBE Proceedings
Volume	23
ISSN (Print)	1680-0737

Conference

Conference	13th International Conference on Biomedical Engineering, ICBME 2008
Country/Territory	Singapore
Period	12/3/08 → 12/6/08

ASJC Scopus Subject Areas

Bioengineering
Biomedical Engineering

Keywords

Barium Strontium Titanate
Electrochemical Sensor
Impedance Spectroscopy
Impedimetric Immunosensor
Surface Modification

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10.1007/978-3-540-92841-6_212

Cite this

@inproceedings{4d120aba82c34cec84b8b9f96858eb7f,

title = "A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate",

abstract = "A novel signal amplification mechanism for impedimetric biosensors is proposed. The proposed mechanism is based on humidity sensing properties of BST composite film and eliminates the need for application of bioactive labels for signal enhancement in amplified impedimetric biosensors. It suggests a good alternative to conventional impedimetric biosensors by improving the detection limit without adding any extra complexity to the system. It is direct and label-free, and can be employed for detection of a wide range of analytes. The sensing capability of the system was exemplified for detection of anti-BSA protein and a low detection limit of 10 ng/ml was obtained.",

keywords = "Barium Strontium Titanate, Electrochemical Sensor, Impedance Spectroscopy, Impedimetric Immunosensor, Surface Modification",

author = "Mahdi Rasouli and Tan, {O. K.} and Sun, {L. L.} and Mao, {B. W.} and Gan, {L. H.}",

year = "2009",

doi = "10.1007/978-3-540-92841-6_212",

language = "English",

isbn = "9783540928409",

series = "IFMBE Proceedings",

pages = "863--866",

booktitle = "13th International Conference on Biomedical Engineering - ICBME 2008",

note = "13th International Conference on Biomedical Engineering, ICBME 2008 ; Conference date: 03-12-2008 Through 06-12-2008",

}

Rasouli, M, Tan, OK, Sun, LL, Mao, BW & Gan, LH 2009, A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate. in 13th International Conference on Biomedical Engineering - ICBME 2008. IFMBE Proceedings, vol. 23, pp. 863-866, 13th International Conference on Biomedical Engineering, ICBME 2008, Singapore, 12/3/08. https://doi.org/10.1007/978-3-540-92841-6_212

TY - GEN

T1 - A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate

AU - Rasouli, Mahdi

AU - Tan, O. K.

AU - Sun, L. L.

AU - Mao, B. W.

AU - Gan, L. H.

PY - 2009

Y1 - 2009

N2 - A novel signal amplification mechanism for impedimetric biosensors is proposed. The proposed mechanism is based on humidity sensing properties of BST composite film and eliminates the need for application of bioactive labels for signal enhancement in amplified impedimetric biosensors. It suggests a good alternative to conventional impedimetric biosensors by improving the detection limit without adding any extra complexity to the system. It is direct and label-free, and can be employed for detection of a wide range of analytes. The sensing capability of the system was exemplified for detection of anti-BSA protein and a low detection limit of 10 ng/ml was obtained.

AB - A novel signal amplification mechanism for impedimetric biosensors is proposed. The proposed mechanism is based on humidity sensing properties of BST composite film and eliminates the need for application of bioactive labels for signal enhancement in amplified impedimetric biosensors. It suggests a good alternative to conventional impedimetric biosensors by improving the detection limit without adding any extra complexity to the system. It is direct and label-free, and can be employed for detection of a wide range of analytes. The sensing capability of the system was exemplified for detection of anti-BSA protein and a low detection limit of 10 ng/ml was obtained.

KW - Barium Strontium Titanate

KW - Electrochemical Sensor

KW - Impedance Spectroscopy

KW - Impedimetric Immunosensor

KW - Surface Modification

UR - http://www.scopus.com/inward/record.url?scp=84891951718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891951718&partnerID=8YFLogxK

U2 - 10.1007/978-3-540-92841-6_212

DO - 10.1007/978-3-540-92841-6_212

M3 - Conference contribution

AN - SCOPUS:84891951718

SN - 9783540928409

T3 - IFMBE Proceedings

SP - 863

EP - 866

BT - 13th International Conference on Biomedical Engineering - ICBME 2008

T2 - 13th International Conference on Biomedical Engineering, ICBME 2008

Y2 - 3 December 2008 through 6 December 2008

ER -

A Label-Free Impedimetric Immunosensor Based on Humidity Sensing Properties of Barium Strontium Titanate

Abstract

Publication series

Conference

ASJC Scopus Subject Areas

Keywords

Access to Document

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