A manganese–ferritin nanocomposite as an ultrasensitive T2 contrast agent

Barindra Sana; Chueh Loo Poh; Sierin Lim

doi:10.1039/c1cc15189d

A manganese–ferritin nanocomposite as an ultrasensitive T₂ contrast agent

Barindra Sana, Chueh Loo Poh, Sierin Lim^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

T₂ contrast is gaining importance in high field strength MRI. We report a strategy for developing a T₂ contrast agent from paramagnetic metal ions synthesized within an engineered protein cage. The manganese–ferritin nanocomposite showed high T₂ relaxivity indicating its potential as an ultrasensitive T₂ contrast agent.

Original language	English
Pages (from-to)	862-864
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	6
DOIs	https://doi.org/10.1039/c1cc15189d
Publication status	Published - Dec 14 2012
Externally published	Yes

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c1cc15189d

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abstract = "T2 contrast is gaining importance in high field strength MRI. We report a strategy for developing a T2 contrast agent from paramagnetic metal ions synthesized within an engineered protein cage. The manganese–ferritin nanocomposite showed high T2 relaxivity indicating its potential as an ultrasensitive T2 contrast agent.",

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AB - T2 contrast is gaining importance in high field strength MRI. We report a strategy for developing a T2 contrast agent from paramagnetic metal ions synthesized within an engineered protein cage. The manganese–ferritin nanocomposite showed high T2 relaxivity indicating its potential as an ultrasensitive T2 contrast agent.

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A manganese–ferritin nanocomposite as an ultrasensitive T₂ contrast agent

Abstract

ASJC Scopus Subject Areas

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