A minimalist approach to stereoselective glycosylation with unprotected donors

Kim Le Mai Hoang; Jing Xi He; Gábor Báti; Mary B. Chan-Park; Xue Wei Liu

doi:10.1038/s41467-017-01073-7

A minimalist approach to stereoselective glycosylation with unprotected donors

Kim Le Mai Hoang, Jing Xi He, Gábor Báti, Mary B. Chan-Park^*, Xue Wei Liu

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Oligosaccharide synthesis is encumbered by multiple protection and deprotection steps. Here, the authors report a protection-free yet stereoselective and regioselective glycosylation strategy using boron-masked glycosyl donors, and demonstrate efficient synthesis of oligosaccharides over a wide substrate scope.

Original language	English
Article number	1146
Journal	Nature Communications
Volume	8
Issue number	1
DOIs	https://doi.org/10.1038/s41467-017-01073-7
Publication status	Published - Dec 1 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 The Author(s).

ASJC Scopus Subject Areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

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10.1038/s41467-017-01073-7

Cite this

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AB - Oligosaccharide synthesis is encumbered by multiple protection and deprotection steps. Here, the authors report a protection-free yet stereoselective and regioselective glycosylation strategy using boron-masked glycosyl donors, and demonstrate efficient synthesis of oligosaccharides over a wide substrate scope.

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A minimalist approach to stereoselective glycosylation with unprotected donors

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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