A novel device for sectioning prostate in correlation to MRI

Ma H. Yun*, Phee S.J. Louis, Thng C. Hua, Tan P. Hoon, Yuen John, Ng W. Sing, Cheng W.S. Chris

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We present a novel slicing device that enables the orientation of fresh or fixed prostate gross pathological sections to be obtained which correspond to Magnetic Resonance Images (MRI). The correlation of histologic preparations and MR images provides insight into biology of disease processes. Based on pre-determined landmarks, the prostate specimen was orientated and sliced in the device in the same manner as the prostate was scanned by MRI. Three phantoms and 11 patients were used to study the accuracy of the slicer. MRI and the pathological sections were examined by both radiologist and pathologist for prominent nodules. The intersection area of nodule on the MRI and pathological slices was calculated. The result shows that the prostate slicing device is fairly accurate and can potentially allow direct correlation between radiological images and histopathology. It has uses in the evaluation of current and future imaging sequences such as magnetic resonance spectroscopy.

Original languageEnglish
Title of host publicationProceedings of the Second IASTED International Conference on Biomechanics
EditorsM.H. Hamza
Pages156-161
Number of pages6
Publication statusPublished - 2004
Externally publishedYes
EventProceedings of the Second IASTED International Conference on Biomechanics - Honolulu, HI, United States
Duration: Aug 23 2004Aug 25 2004

Publication series

NameProceedings of the Second IASTED International Conference on Biomechanics

Conference

ConferenceProceedings of the Second IASTED International Conference on Biomechanics
Country/TerritoryUnited States
CityHonolulu, HI
Period8/23/048/25/04

ASJC Scopus Subject Areas

  • General Engineering

Keywords

  • Area calculation
  • MRI
  • Pathological section
  • Slicing device, prostate
  • Validation

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