A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

Teck Peng Loh; Xu Ran Li

doi:10.1016/S0040-4039(96)02434-3

A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

Teck Peng Loh^*, Xu Ran Li

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

The indium-mediated allylation reaction of aldehydes with 1,1,1 -trifluor and bromo-2-butene in water afforded an important trifluoromethylated building black β-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity.

Original language	English
Pages (from-to)	869-872
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	5
DOIs	https://doi.org/10.1016/S0040-4039(96)02434-3
Publication status	Published - Feb 3 1997
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(96)02434-3

Cite this

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title = "A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water",

abstract = "The indium-mediated allylation reaction of aldehydes with 1,1,1 -trifluor and bromo-2-butene in water afforded an important trifluoromethylated building black β-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity.",

author = "Loh, \{Teck Peng\} and Li, \{Xu Ran\}",

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T1 - A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

AU - Loh, Teck Peng

AU - Li, Xu Ran

PY - 1997/2/3

Y1 - 1997/2/3

N2 - The indium-mediated allylation reaction of aldehydes with 1,1,1 -trifluor and bromo-2-butene in water afforded an important trifluoromethylated building black β-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity.

AB - The indium-mediated allylation reaction of aldehydes with 1,1,1 -trifluor and bromo-2-butene in water afforded an important trifluoromethylated building black β-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity.

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U2 - 10.1016/S0040-4039(96)02434-3

DO - 10.1016/S0040-4039(96)02434-3

M3 - Article

AN - SCOPUS:0031016069

SN - 0040-4039

VL - 38

SP - 869

EP - 872

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 5

ER -

A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

Abstract

ASJC Scopus Subject Areas

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