A simple and practical synthesis of α-trifluoromethylated alcohols in water

Teck Peng Loh*, Xu Ran Li

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

A simple and practical preparation of α-trifluoromethylated alcohols in water via indium-mediated allylation reaction and tin-mediated indium trichloride-promoted allylation reaction of trifluoroacetaldehyde hydrate and its ethyl hemiacetal is described in this paper.

Original languageEnglish
Pages (from-to)5611-5622
Number of pages12
JournalTetrahedron
Volume55
Issue number17
DOIs
Publication statusPublished - Apr 23 1999
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Keywords

  • α-Trifluoromethylated alcohols
  • Allylation
  • Indium
  • Water

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