A synthesis of 5-hydroxysedamine using hydroformylation

Roderick W. Bates; Nur Filza Bte Mohamed Aslam; Chi H. Tang; Oliver Simon

doi:10.1016/j.tet.2014.02.001

A synthesis of 5-hydroxysedamine using hydroformylation

Roderick W. Bates^*, Nur Filza Bte Mohamed Aslam, Chi H. Tang, Oliver Simon

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.

Original language	English
Pages (from-to)	2134-2140
Number of pages	7
Journal	Tetrahedron
Volume	70
Issue number	12
DOIs	https://doi.org/10.1016/j.tet.2014.02.001
Publication status	Published - Mar 25 2014
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tet.2014.02.001

Cite this

@article{9251466306774e23b2a9721295ddde1b,

title = "A synthesis of 5-hydroxysedamine using hydroformylation",

abstract = "A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.",

author = "Bates, {Roderick W.} and Aslam, {Nur Filza Bte Mohamed} and Tang, {Chi H.} and Oliver Simon",

year = "2014",

month = mar,

day = "25",

doi = "10.1016/j.tet.2014.02.001",

language = "English",

volume = "70",

pages = "2134--2140",

journal = "Tetrahedron",

issn = "0040-4020",

publisher = "Elsevier Limited",

number = "12",

}

TY - JOUR

T1 - A synthesis of 5-hydroxysedamine using hydroformylation

AU - Bates, Roderick W.

AU - Aslam, Nur Filza Bte Mohamed

AU - Tang, Chi H.

AU - Simon, Oliver

PY - 2014/3/25

Y1 - 2014/3/25

N2 - A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.

AB - A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.

UR - http://www.scopus.com/inward/record.url?scp=84896710959&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896710959&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2014.02.001

DO - 10.1016/j.tet.2014.02.001

M3 - Article

AN - SCOPUS:84896710959

SN - 0040-4020

VL - 70

SP - 2134

EP - 2140

JO - Tetrahedron

JF - Tetrahedron

IS - 12

ER -

A synthesis of 5-hydroxysedamine using hydroformylation

Abstract

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this