A synthesis of cyanolide a by intramolecular oxa-Michael addition

Roderick W. Bates*, Tee Guan Lek

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

A synthesis of cyanolide A, a diolide natural product, has been achieved using a diastereoselective Barbier reaction, early-stage glycosylation, and intramolecular oxa-Michael addition to form the THP ring.

Original languageEnglish
Article numberSS-2014-T0094-OP
Pages (from-to)1731-1738
Number of pages8
JournalSynthesis
Volume46
Issue number13
DOIs
Publication statusPublished - Jul 2014
Externally publishedYes

ASJC Scopus Subject Areas

  • Catalysis
  • Organic Chemistry

Keywords

  • Barbier reaction
  • cyclisation
  • glycosylation
  • Michael addition
  • natural products

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