Alkaline-Earth Metal Catalyzed Dehydrative Allylic Alkylation

Peizhong Xie; Shuangshuang Li; Yanan Liu; Xinying Cai; Jinyu Wang; Xiaobo Yang; Teck Peng Loh

doi:10.1021/acs.orglett.9b03730

Alkaline-Earth Metal Catalyzed Dehydrative Allylic Alkylation

Peizhong Xie^*, Shuangshuang Li, Yanan Liu, Xinying Cai, Jinyu Wang, Xiaobo Yang, Teck Peng Loh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

An alkaline-earth metal catalytic system for environmentally benign allylic alkylation was developed. Allylic alcohols can be utilized directly at room temperature in this transition-metal-free process, producing water as the only byproduct. A variety of allylic compounds, including the ones containing all-carbonyl quaternary centers, can be obtained with high yields.

Original language	English
Pages (from-to)	31-35
Number of pages	5
Journal	Organic Letters
Volume	22
Issue number	1
DOIs	https://doi.org/10.1021/acs.orglett.9b03730
Publication status	Published - Jan 3 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
Copyright © 2019 American Chemical Society.

ASJC Scopus Subject Areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/acs.orglett.9b03730

Cite this

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title = "Alkaline-Earth Metal Catalyzed Dehydrative Allylic Alkylation",

abstract = "An alkaline-earth metal catalytic system for environmentally benign allylic alkylation was developed. Allylic alcohols can be utilized directly at room temperature in this transition-metal-free process, producing water as the only byproduct. A variety of allylic compounds, including the ones containing all-carbonyl quaternary centers, can be obtained with high yields.",

author = "Peizhong Xie and Shuangshuang Li and Yanan Liu and Xinying Cai and Jinyu Wang and Xiaobo Yang and Loh, {Teck Peng}",

note = "Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",

year = "2020",

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doi = "10.1021/acs.orglett.9b03730",

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T1 - Alkaline-Earth Metal Catalyzed Dehydrative Allylic Alkylation

AU - Xie, Peizhong

AU - Li, Shuangshuang

AU - Liu, Yanan

AU - Cai, Xinying

AU - Wang, Jinyu

AU - Yang, Xiaobo

AU - Loh, Teck Peng

PY - 2020/1/3

Y1 - 2020/1/3

N2 - An alkaline-earth metal catalytic system for environmentally benign allylic alkylation was developed. Allylic alcohols can be utilized directly at room temperature in this transition-metal-free process, producing water as the only byproduct. A variety of allylic compounds, including the ones containing all-carbonyl quaternary centers, can be obtained with high yields.

AB - An alkaline-earth metal catalytic system for environmentally benign allylic alkylation was developed. Allylic alcohols can be utilized directly at room temperature in this transition-metal-free process, producing water as the only byproduct. A variety of allylic compounds, including the ones containing all-carbonyl quaternary centers, can be obtained with high yields.

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U2 - 10.1021/acs.orglett.9b03730

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Alkaline-Earth Metal Catalyzed Dehydrative Allylic Alkylation

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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