An alternative method for evaluating stabilities of DNA hairpin structures

Hao Zhang, Sai Ba, Sarajane Co Co, Jasmine Yiqin Lee, Juanjuan Guo, Ruijuan Ye, Zhaoxun Liang, Dejian Huang, Tianhu Li*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

We have developed an alternative methodology for determining the stabilities of DNA hairpin structures based on a specially designed oligonucleotide template and the T4 DNA ligase. This method was systematically tested by evaluation of DNA hairpin stabilities when varying the loop size and the nature of the loop sequence.

Original languageEnglish
Pages (from-to)1314-1316
Number of pages3
JournalBulletin of the Chemical Society of Japan
Volume88
Issue number9
DOIs
Publication statusPublished - 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015 The Chemical Society of Japan.

ASJC Scopus Subject Areas

  • General Chemistry

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