An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane

Teck Peng Loh; Jian Rong Zhou; Xu Ran Li

doi:10.1016/S0040-4039(99)01976-0

An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane

Teck Peng Loh^*, Jian Rong Zhou, Xu Ran Li

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

An enantioselective indium-mediated addition reaction of allylic bromides to carbonyl compounds was achieved in dichloromethane in the presence of (-)-cinchonidine. The desired products were obtained in moderate to excellent yields and with up to 75% enantioselectivity.

Original language	English
Pages (from-to)	9333-9336
Number of pages	4
Journal	Tetrahedron Letters
Volume	40
Issue number	52
DOIs	https://doi.org/10.1016/S0040-4039(99)01976-0
Publication status	Published - Dec 24 1999
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Allylation
Carbonyl
Enantioselectivity
Indium
Trifluoromethyl

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10.1016/S0040-4039(99)01976-0

Cite this

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title = "An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane",

abstract = "An enantioselective indium-mediated addition reaction of allylic bromides to carbonyl compounds was achieved in dichloromethane in the presence of (-)-cinchonidine. The desired products were obtained in moderate to excellent yields and with up to 75% enantioselectivity.",

keywords = "Allylation, Carbonyl, Enantioselectivity, Indium, Trifluoromethyl",

author = "Loh, {Teck Peng} and Zhou, {Jian Rong} and Li, {Xu Ran}",

year = "1999",

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T1 - An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane

AU - Loh, Teck Peng

AU - Zhou, Jian Rong

AU - Li, Xu Ran

PY - 1999/12/24

Y1 - 1999/12/24

N2 - An enantioselective indium-mediated addition reaction of allylic bromides to carbonyl compounds was achieved in dichloromethane in the presence of (-)-cinchonidine. The desired products were obtained in moderate to excellent yields and with up to 75% enantioselectivity.

AB - An enantioselective indium-mediated addition reaction of allylic bromides to carbonyl compounds was achieved in dichloromethane in the presence of (-)-cinchonidine. The desired products were obtained in moderate to excellent yields and with up to 75% enantioselectivity.

KW - Allylation

KW - Carbonyl

KW - Enantioselectivity

KW - Indium

KW - Trifluoromethyl

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U2 - 10.1016/S0040-4039(99)01976-0

DO - 10.1016/S0040-4039(99)01976-0

M3 - Article

AN - SCOPUS:0033601395

SN - 0040-4039

VL - 40

SP - 9333

EP - 9336

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -

An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane

Abstract

ASJC Scopus Subject Areas

Keywords

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