TY - GEN
T1 - An in vivo evaluation of a bioactive composite matrix for dermal regeneration
AU - Louis, J.
AU - Ng, K. W.
AU - Achuth, H. N.
AU - Lu, Jia
AU - Moochhala, S.
AU - Hutmacher, D. W.
PY - 2004
Y1 - 2004
N2 - An in vitro study to examine cell attachment and proliferation was carried out using human dermal fibroblasts on the PLGA-collagen hybrid mesh. Cell attachment, morphology, and viability were analyzed using scanning electron microscopy (SEM), light microscopy and confocal laser microscopy. It was observed that a composite matrix was made by freeze-drying collagen, within a PLGA knitted mesh in order to circumvent some of the disadvantages of each group of materials. The results show that meshes were capable of supporting cell attachment, proliferation and neotissue formation.
AB - An in vitro study to examine cell attachment and proliferation was carried out using human dermal fibroblasts on the PLGA-collagen hybrid mesh. Cell attachment, morphology, and viability were analyzed using scanning electron microscopy (SEM), light microscopy and confocal laser microscopy. It was observed that a composite matrix was made by freeze-drying collagen, within a PLGA knitted mesh in order to circumvent some of the disadvantages of each group of materials. The results show that meshes were capable of supporting cell attachment, proliferation and neotissue formation.
KW - Bioactive material
KW - Dermal regeneration
KW - Poly (lactic-co-glycolic acid)
UR - http://www.scopus.com/inward/record.url?scp=13844272290&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=13844272290&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:13844272290
SN - 1877040193
SN - 9781877040191
T3 - Transactions - 7th World Biomaterials Congress
SP - 1071
BT - Transactions - 7th World Biomaterials Congress
T2 - Transactions - 7th World Biomaterials Congress
Y2 - 17 May 2004 through 21 May 2004
ER -