An unusual approach to the synthesis of enantiomerically cis linear homoallylic alcohols based on the steric interaction mechanism of camphor scaffold

Chi Lik Ken Lee, Cheng Hsia Angeline Lee, Kui Thong Tan, Teck Peng Loh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

Camphor is used as the chiral auxiliary for the enantioselective synthesis of cis linear homoallylic alcohols. A range of catalysts, aldehydes, and solvents were investigated to obtain the optimum yield, enantioselectivity, and cis olefinic geometry.

Original languageEnglish
Pages (from-to)1281-1283
Number of pages3
JournalOrganic Letters
Volume6
Issue number8
DOIs
Publication statusPublished - Apr 15 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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