Anti -Selective aminofluorination of alkenes with amidines mediated by hypervalent iodine(III) reagents

Hui Chen, Atsushi Kaga, Shunsuke Chiba*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

anti-Selective aminofluorination of alkenes with amidines was enabled by hypervalent iodine(iii) reagents, affording 4-fluoroalkyl-2-imidazolines. Further reductive ring-opening of the 2-imidazoline moiety could deliver highly functionalized 3-fluoropropane-1,2-diamine derivatives.

Original languageEnglish
Pages (from-to)5481-5485
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume14
Issue number24
DOIs
Publication statusPublished - 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2016.

ASJC Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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