Asymmetric carbene catalysis: A brief highlight of developments in the past decade

Jia Lei Yan; Hongling Wang; Yonggui Robin Chi

doi:10.1002/9781119736424.ch6

Asymmetric carbene catalysis: A brief highlight of developments in the past decade

Jia Lei Yan^*, Hongling Wang, Yonggui Robin Chi

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

This chapter summarizes the new advancements of N-heterocyclic carbene (NHC) organocatalysis in the recent decade (roughly between 2010 and 2020). Particular focus is drawn to the basic activation and reaction modes enabled by NHC as a key catalyst. Examples of these key development include NHC-catalyzed reactions beyond simple aldehydes to unsaturated aldehydes and functionalized aldehydes as substrates, activation of carboxylic esters for asymmetric reactions, single-electro-transfer radical reactions, cooperative catalysis involve NHC and other catalysts such as transition metals, and applications of NHC-catalyzed reactions in the synthesis of sophisticated molecules.

Original language	English
Title of host publication	Catalytic Asymmetric Synthesis
Publisher	wiley
Pages	199-242
Number of pages	44
ISBN (Electronic)	9781119736424
ISBN (Print)	9781119734857
DOIs	https://doi.org/10.1002/9781119736424.ch6
Publication status	Published - Jun 3 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022 by John Wiley & Sons, Inc. All rights reserved.

ASJC Scopus Subject Areas

General Chemistry
General Chemical Engineering

Keywords

Carboxylic ester activation
Cooperative catalysis
N-heterocyclic carbene
New activation mode
New reactions
Single-electron transfer
Synthetic application

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10.1002/9781119736424.ch6

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abstract = "This chapter summarizes the new advancements of N-heterocyclic carbene (NHC) organocatalysis in the recent decade (roughly between 2010 and 2020). Particular focus is drawn to the basic activation and reaction modes enabled by NHC as a key catalyst. Examples of these key development include NHC-catalyzed reactions beyond simple aldehydes to unsaturated aldehydes and functionalized aldehydes as substrates, activation of carboxylic esters for asymmetric reactions, single-electro-transfer radical reactions, cooperative catalysis involve NHC and other catalysts such as transition metals, and applications of NHC-catalyzed reactions in the synthesis of sophisticated molecules.",

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AU - Chi, Yonggui Robin

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Y1 - 2022/6/3

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AB - This chapter summarizes the new advancements of N-heterocyclic carbene (NHC) organocatalysis in the recent decade (roughly between 2010 and 2020). Particular focus is drawn to the basic activation and reaction modes enabled by NHC as a key catalyst. Examples of these key development include NHC-catalyzed reactions beyond simple aldehydes to unsaturated aldehydes and functionalized aldehydes as substrates, activation of carboxylic esters for asymmetric reactions, single-electro-transfer radical reactions, cooperative catalysis involve NHC and other catalysts such as transition metals, and applications of NHC-catalyzed reactions in the synthesis of sophisticated molecules.

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KW - Cooperative catalysis

KW - N-heterocyclic carbene

KW - New activation mode

KW - New reactions

KW - Single-electron transfer

KW - Synthetic application

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Asymmetric carbene catalysis: A brief highlight of developments in the past decade

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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