Abstract
A novel catalytic asymmetric P-C bond formation between phosphinates/phosphine oxide and allylic carbonates was developed. This methodology could not only afford a variety of functionalized adjacent P,C-stereogenic phosphorus compounds in high yields with high regio- and diastereoselectivities but also provide an alternative strategy to access enantiomerically enriched (SP)-phosphinates through kinetic resolution. New strategy for adjacent P,C-stereogenic phosphorus compounds: A novel catalytic asymmetric P-C bond formation between phosphinates/phosphine oxide and allylic carbonates was developed. This methodology could not only afford a variety of functionalized adjacent P,C-stereogenic phosphorus compounds in high yields with high regio- and diastereoselectivities but also provide an alternative strategy to access enantiomerically enriched (SP)-phosphinates through kinetic resolution.
| Original language | English |
|---|---|
| Pages (from-to) | 1353-1356 |
| Number of pages | 4 |
| Journal | Chemistry - An Asian Journal |
| Volume | 11 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - May 6 2016 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
ASJC Scopus Subject Areas
- Biochemistry
- General Chemistry
- Organic Chemistry
Keywords
- 1,3-bisphosphinylpropanes
- kinetic resolution
- organocatalysis
- P-C bond formation
- P-stereogenic compounds