Background-free fibre optic Brillouin probe for remote mapping of micromechanics

Yuchen Xiang, Carin Basirun, Joshua Chou, Majid E. Warkiani, Peter Török, Yingying Wang, Shoufei Gao, Irina V. Kabakova*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Brillouin imaging (BI) has become a valuable tool for micromechanical material characterisation, thanks to extensive progress in instrumentation in the last few decades. This powerful technique is contactless and label-free, thus making it especially suitable for biomedical applications. Nonetheless, to fully harness the non-contact and non-destructive nature of BI, transformational changes in instrumentation are still needed to extend the technology’s utility into the domain of in vivo and in situ operation, which we foresee to be particularly crucial for wide spread usage of BI, e.g. in medical diagnostics and pathology screening. This work addresses this challenge by presenting the first demonstration of a fibre-optic Brillouin probe, capable of mapping the micromechanical properties of a tissue-mimicking phantom. This is achieved through combination of miniaturised optical design, advanced hollow-core fibre fabrication and high-resolution 3D printing. Our prototype probe is compact, background-free and possesses the highest collection efficiency to date, thus providing the foundation of a fibre-based Brillouin device for remote, in situ measurements in challenging and otherwise difficult-to-reach environments in biomedical, material science and industrial applications.

Original languageEnglish
Pages (from-to)6687-6698
Number of pages12
JournalBiomedical Optics Express
Volume11
Issue number11
DOIs
Publication statusPublished - Nov 1 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.

ASJC Scopus Subject Areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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