BF3-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

Zhi Yuan Gao; Yu He; Lan Yang Li; Jie Sheng Tian; Teck Peng Loh

doi:10.1039/d2qo00405d

BF₃-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

Zhi Yuan Gao, Yu He, Lan Yang Li, Jie Sheng Tian^*, Teck Peng Loh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

An efficient BF₃-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.

Original language	English
Pages (from-to)	3317-3321
Number of pages	5
Journal	Organic Chemistry Frontiers
Volume	9
Issue number	12
DOIs	https://doi.org/10.1039/d2qo00405d
Publication status	Published - May 12 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022 The Royal Society of Chemistry

ASJC Scopus Subject Areas

Organic Chemistry

Access to Document

10.1039/d2qo00405d

Cite this

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title = "BF3-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles",

abstract = "An efficient BF3-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.",

author = "Gao, {Zhi Yuan} and Yu He and Li, {Lan Yang} and Tian, {Jie Sheng} and Loh, {Teck Peng}",

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AU - Gao, Zhi Yuan

AU - He, Yu

AU - Li, Lan Yang

AU - Tian, Jie Sheng

AU - Loh, Teck Peng

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Y1 - 2022/5/12

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