Bioimaging in the mid-infrared using an organometallic carbonyl tag

Voon Kong Kien, Wee Chew, Lina Hsiu Kim Lim, Yip Fan Wai, Kee Leong Weng*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)

Abstract

Two stable and water-soluble organometallic carbonyl cluster derivatives have been prepared and shown to enter the cell with ease. The CO stretching vibrations afford strong mid-infrared signals which have been demonstrated, for the first time, to be of utility in cell imaging via an IR microscope.

Original languageEnglish
Pages (from-to)1370-1374
Number of pages5
JournalBioconjugate Chemistry
Volume18
Issue number5
DOIs
Publication statusPublished - 2007
Externally publishedYes

ASJC Scopus Subject Areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • Pharmacology
  • Pharmaceutical Science
  • Organic Chemistry

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