Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

Ali Ghadban; Anansa S. Ahmed; Yuan Ping; Ricardo Ramos; Najmul Arfin; Bram Cantaert; Raju V. Ramanujan; Ali Miserez

doi:10.1039/c5cc08617e

Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

Ali Ghadban, Anansa S. Ahmed, Yuan Ping, Ricardo Ramos, Najmul Arfin, Bram Cantaert, Raju V. Ramanujan, Ali Miserez^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

81 Citations (Scopus)

Abstract

We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe³⁺ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.

Original language	English
Pages (from-to)	697-700
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	4
DOIs	https://doi.org/10.1039/c5cc08617e
Publication status	Published - 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2016.

ASJC Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c5cc08617e

Cite this

@article{9dc422c794eb442ca2929eaac60f58ce,

title = "Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties",

abstract = "We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe3+ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.",

author = "Ali Ghadban and Ahmed, {Anansa S.} and Yuan Ping and Ricardo Ramos and Najmul Arfin and Bram Cantaert and Ramanujan, {Raju V.} and Ali Miserez",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

doi = "10.1039/c5cc08617e",

language = "English",

volume = "52",

pages = "697--700",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "4",

}

TY - JOUR

T1 - Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

AU - Ghadban, Ali

AU - Ahmed, Anansa S.

AU - Ping, Yuan

AU - Ramos, Ricardo

AU - Arfin, Najmul

AU - Cantaert, Bram

AU - Ramanujan, Raju V.

AU - Miserez, Ali

PY - 2016

Y1 - 2016

N2 - We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe3+ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.

AB - We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe3+ ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.

UR - http://www.scopus.com/inward/record.url?scp=85000765412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85000765412&partnerID=8YFLogxK

U2 - 10.1039/c5cc08617e

DO - 10.1039/c5cc08617e

M3 - Article

C2 - 26558317

AN - SCOPUS:85000765412

SN - 1359-7345

VL - 52

SP - 697

EP - 700

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this