Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

Chengli Mou; Jichang Wu; Zhijian Huang; Jun Sun; Zhichao Jin; Yonggui Robin Chi

doi:10.1039/c7cc08039e

Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

Chengli Mou, Jichang Wu, Zhijian Huang, Jun Sun, Zhichao Jin, Yonggui Robin Chi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

A carbene-catalyzed LUMO activation of α,β-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is involved in the key step of the reaction.

Original language	English
Pages (from-to)	13359-13362
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	100
DOIs	https://doi.org/10.1039/c7cc08039e
Publication status	Published - 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 The Royal Society of Chemistry.

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "A carbene-catalyzed LUMO activation of α,β-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is involved in the key step of the reaction.",

author = "Chengli Mou and Jichang Wu and Zhijian Huang and Jun Sun and Zhichao Jin and Chi, {Yonggui Robin}",

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T1 - Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

AU - Mou, Chengli

AU - Wu, Jichang

AU - Huang, Zhijian

AU - Sun, Jun

AU - Jin, Zhichao

AU - Chi, Yonggui Robin

PY - 2017

Y1 - 2017

N2 - A carbene-catalyzed LUMO activation of α,β-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is involved in the key step of the reaction.

AB - A carbene-catalyzed LUMO activation of α,β-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is involved in the key step of the reaction.

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U2 - 10.1039/c7cc08039e

DO - 10.1039/c7cc08039e

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AN - SCOPUS:85038414559

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JO - Chemical Communications

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ER -

Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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