Catalytic enantioselective allylation of aldehydes via a moisture-tolerant chiral BINOL-In(III) complex

Yong Chua Teo; Ee Ling Goh; Teck Peng Loh

doi:10.1016/j.tetlet.2005.07.064

Catalytic enantioselective allylation of aldehydes via a moisture-tolerant chiral BINOL-In(III) complex

Yong Chua Teo, Ee Ling Goh, Teck Peng Loh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A moisture-tolerant chiral indium complex has been developed to effect good enantioselectivities in the addition of allyltributylstannanes to aldehydes. The allylation of a variety of aromatic, α,β-unsaturated and aliphatic aldehydes resulted in both moderate to good yields and high enantioselectivities (up to 86% ee).

Original language	English
Pages (from-to)	6209-6211
Number of pages	3
Journal	Tetrahedron Letters
Volume	46
Issue number	37
DOIs	https://doi.org/10.1016/j.tetlet.2005.07.064
Publication status	Published - Sept 12 2005
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Catalytic
Chiral indium complex
Enantioselective allylation
Moisture-tolerant

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10.1016/j.tetlet.2005.07.064

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title = "Catalytic enantioselective allylation of aldehydes via a moisture-tolerant chiral BINOL-In(III) complex",

abstract = "A moisture-tolerant chiral indium complex has been developed to effect good enantioselectivities in the addition of allyltributylstannanes to aldehydes. The allylation of a variety of aromatic, α,β-unsaturated and aliphatic aldehydes resulted in both moderate to good yields and high enantioselectivities (up to 86\% ee).",

keywords = "Catalytic, Chiral indium complex, Enantioselective allylation, Moisture-tolerant",

author = "Teo, \{Yong Chua\} and Goh, \{Ee Ling\} and Loh, \{Teck Peng\}",

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doi = "10.1016/j.tetlet.2005.07.064",

language = "English",

volume = "46",

pages = "6209--6211",

journal = "Tetrahedron Letters",

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T1 - Catalytic enantioselective allylation of aldehydes via a moisture-tolerant chiral BINOL-In(III) complex

AU - Teo, Yong Chua

AU - Goh, Ee Ling

AU - Loh, Teck Peng

PY - 2005/9/12

Y1 - 2005/9/12

N2 - A moisture-tolerant chiral indium complex has been developed to effect good enantioselectivities in the addition of allyltributylstannanes to aldehydes. The allylation of a variety of aromatic, α,β-unsaturated and aliphatic aldehydes resulted in both moderate to good yields and high enantioselectivities (up to 86% ee).

AB - A moisture-tolerant chiral indium complex has been developed to effect good enantioselectivities in the addition of allyltributylstannanes to aldehydes. The allylation of a variety of aromatic, α,β-unsaturated and aliphatic aldehydes resulted in both moderate to good yields and high enantioselectivities (up to 86% ee).

KW - Catalytic

KW - Chiral indium complex

KW - Enantioselective allylation

KW - Moisture-tolerant

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DO - 10.1016/j.tetlet.2005.07.064

M3 - Article

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SN - 0040-4039

VL - 46

SP - 6209

EP - 6211

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 37

ER -

Catalytic enantioselective allylation of aldehydes via a moisture-tolerant chiral BINOL-In(III) complex

Abstract

ASJC Scopus Subject Areas

Keywords

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