Catalytic enantioselective Mukaiyama aldol reaction via a chiral indium(III)-pybox complex

Fan Fu; Yong Chua Teo; Teck Peng Loh

doi:10.1016/j.tetlet.2006.04.029

Catalytic enantioselective Mukaiyama aldol reaction via a chiral indium(III)-pybox complex

Fan Fu, Yong Chua Teo, Teck Peng Loh^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A chiral indium(III) complex prepared from indium triflate and a pybox ligand has been developed to give good yields and enantioselectivities (up to 92% ee) in the addition of (1-methoxy-2-methyl-propenyloxy)-trimethylsilane to various aromatic and aliphatic aldehydes via the Mukaiyama aldol reaction.

Original language	English
Pages (from-to)	4267-4269
Number of pages	3
Journal	Tetrahedron Letters
Volume	47
Issue number	25
DOIs	https://doi.org/10.1016/j.tetlet.2006.04.029
Publication status	Published - Jun 19 2006
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Catalytic
Chiral indium complex
Enantioselective Mukaiyama aldol

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10.1016/j.tetlet.2006.04.029

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abstract = "A chiral indium(III) complex prepared from indium triflate and a pybox ligand has been developed to give good yields and enantioselectivities (up to 92\% ee) in the addition of (1-methoxy-2-methyl-propenyloxy)-trimethylsilane to various aromatic and aliphatic aldehydes via the Mukaiyama aldol reaction.",

keywords = "Catalytic, Chiral indium complex, Enantioselective Mukaiyama aldol",

author = "Fan Fu and Teo, \{Yong Chua\} and Loh, \{Teck Peng\}",

year = "2006",

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doi = "10.1016/j.tetlet.2006.04.029",

language = "English",

volume = "47",

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journal = "Tetrahedron Letters",

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AU - Fu, Fan

AU - Teo, Yong Chua

AU - Loh, Teck Peng

PY - 2006/6/19

Y1 - 2006/6/19

N2 - A chiral indium(III) complex prepared from indium triflate and a pybox ligand has been developed to give good yields and enantioselectivities (up to 92% ee) in the addition of (1-methoxy-2-methyl-propenyloxy)-trimethylsilane to various aromatic and aliphatic aldehydes via the Mukaiyama aldol reaction.

AB - A chiral indium(III) complex prepared from indium triflate and a pybox ligand has been developed to give good yields and enantioselectivities (up to 92% ee) in the addition of (1-methoxy-2-methyl-propenyloxy)-trimethylsilane to various aromatic and aliphatic aldehydes via the Mukaiyama aldol reaction.

KW - Catalytic

KW - Chiral indium complex

KW - Enantioselective Mukaiyama aldol

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M3 - Article

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VL - 47

SP - 4267

EP - 4269

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 25

ER -

Catalytic enantioselective Mukaiyama aldol reaction via a chiral indium(III)-pybox complex

Abstract

ASJC Scopus Subject Areas

Keywords

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