Abstract
An environmentally friendly method for the cross aldol reaction of silyl enol ethers and ketene silyl acetal with various aldehydes using montmorillonite K10 is described. Cheap and commercially available montmorillonite K10 can be used without the need of an ion exchange process under solvent-free conditions or in water. Hydrate of aldehydes such as glyoxylic acid can be used directly. Thermal treatment of K10 increased the catalytic activity. The catalytic activity was supposed due to the properties of the structure of K10 and its inherent Bronsted acidity.
| Original language | English |
|---|---|
| Pages (from-to) | 10789-10802 |
| Number of pages | 14 |
| Journal | Tetrahedron |
| Volume | 55 |
| Issue number | 35 |
| DOIs | |
| Publication status | Published - Aug 27 1999 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Keywords
- Aldehydes
- Aldol Reactions
- Clays
- Environmentally Friendly
- Water