Colorimetric Detection of Creatinine Based on Plasmonic Nanoparticles via Synergistic Coordination Chemistry

Jianjun Du; Bowen Zhu; Wan Ru Leow; Shi Chen; Tze Chien Sum; Xiaojun Peng; Xiaodong Chen

doi:10.1002/smll.201403369

Colorimetric Detection of Creatinine Based on Plasmonic Nanoparticles via Synergistic Coordination Chemistry

Jianjun Du, Bowen Zhu, Wan Ru Leow, Shi Chen, Tze Chien Sum, Xiaojun Peng^*, Xiaodong Chen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Abstract

A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg²⁺ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.

Original language	English
Pages (from-to)	4104-4110
Number of pages	7
Journal	Small
Volume	11
Issue number	33
DOIs	https://doi.org/10.1002/smll.201403369
Publication status	Published - Sept 1 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

ASJC Scopus Subject Areas

Biotechnology
General Chemistry
Biomaterials
General Materials Science
Engineering (miscellaneous)

Keywords

colorimetric assay
creatinine detection
plasmonic nanoparticle
synergistic coordination

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10.1002/smll.201403369

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abstract = "A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.",

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author = "Jianjun Du and Bowen Zhu and Leow, {Wan Ru} and Shi Chen and Sum, {Tze Chien} and Xiaojun Peng and Xiaodong Chen",

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AU - Du, Jianjun

AU - Zhu, Bowen

AU - Leow, Wan Ru

AU - Chen, Shi

AU - Sum, Tze Chien

AU - Peng, Xiaojun

AU - Chen, Xiaodong

PY - 2015/9/1

Y1 - 2015/9/1

N2 - A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.

AB - A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.

KW - colorimetric assay

KW - creatinine detection

KW - plasmonic nanoparticle

KW - synergistic coordination

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Colorimetric Detection of Creatinine Based on Plasmonic Nanoparticles via Synergistic Coordination Chemistry

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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