Conjugated polyelectrolytes for label-free visual detection of heparin

Kanyi Pu; Ruoyu Zhan; Jing Liang; Bin Liu

doi:10.1007/s11426-011-4241-y

Conjugated polyelectrolytes for label-free visual detection of heparin

Kanyi Pu, Ruoyu Zhan, Jing Liang, Bin Liu^*

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Conjugated polyelectrolytes (CPEs), with electron-delocalized backbones and charged ionic side chains, are unique sensory materials for the construction of optical biosensors. In this feature article, CPE-based visual detection of heparin is summarized. Three CPE-based heparin probes, including ratiometric, light-up and colormetric probes, are discussed in terms of molecular design, detection selectivity and quantification capability. The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing.

Original language	English
Pages (from-to)	567-574
Number of pages	8
Journal	Science China Chemistry
Volume	54
Issue number	4
DOIs	https://doi.org/10.1007/s11426-011-4241-y
Publication status	Published - Apr 2011
Externally published	Yes

ASJC Scopus Subject Areas

General Chemistry

Keywords

conjugated polyelectrolyte
fluorescence resonance energy transfer
heparin
sensor

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10.1007/s11426-011-4241-y

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abstract = "Conjugated polyelectrolytes (CPEs), with electron-delocalized backbones and charged ionic side chains, are unique sensory materials for the construction of optical biosensors. In this feature article, CPE-based visual detection of heparin is summarized. Three CPE-based heparin probes, including ratiometric, light-up and colormetric probes, are discussed in terms of molecular design, detection selectivity and quantification capability. The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing.",

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AU - Zhan, Ruoyu

AU - Liang, Jing

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AB - Conjugated polyelectrolytes (CPEs), with electron-delocalized backbones and charged ionic side chains, are unique sensory materials for the construction of optical biosensors. In this feature article, CPE-based visual detection of heparin is summarized. Three CPE-based heparin probes, including ratiometric, light-up and colormetric probes, are discussed in terms of molecular design, detection selectivity and quantification capability. The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing.

KW - conjugated polyelectrolyte

KW - fluorescence resonance energy transfer

KW - heparin

KW - sensor

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Conjugated polyelectrolytes for label-free visual detection of heparin

Abstract

ASJC Scopus Subject Areas

Keywords

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