Controlled release systems designed for regenerative medicine

K. W. Leong; I. C. Liao; E. Yim; S. Lim; A. Wan; J. Wen; S. Y. Chew; K. N. Chua; S. Ramakrishna; H. Q. Mao

Controlled release systems designed for regenerative medicine

K. W. Leong^*, I. C. Liao, E. Yim, S. Lim, A. Wan, J. Wen, S. Y. Chew, K. N. Chua, S. Ramakrishna, H. Q. Mao

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The features of two fibrous controlled release systems where the drug-loaded fibers are fabricated by electrospinning and polyelectrolyte complexation (PEC) were investigated. The controlled release behavior of drugs from the fibers comprising the biodegradable copolymer of polycaprolactone (PCL) and poly(ethylphosphate) (PCLEEP) was also investigated. The copolymers were synthesized through ring-opening polymerization of caprolactone and ethyl ethylene phosphate (EEP). The results show that delicate compounds such as proteins can better retain their bioactivity in encapsulation process involving PEC.

Original language	English
Title of host publication	Transactions - 7th World Biomaterials Congress
Pages	189
Number of pages	1
Publication status	Published - 2004
Externally published	Yes
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: May 17 2004 → May 21 2004

Publication series

Name	Transactions - 7th World Biomaterials Congress

Conference

Conference	Transactions - 7th World Biomaterials Congress
Country/Territory	Australia
City	Sydney
Period	5/17/04 → 5/21/04

ASJC Scopus Subject Areas

General Engineering

Cite this

@inproceedings{b934f02b5b154d25b8e446b3e1431477,

title = "Controlled release systems designed for regenerative medicine",

abstract = "The features of two fibrous controlled release systems where the drug-loaded fibers are fabricated by electrospinning and polyelectrolyte complexation (PEC) were investigated. The controlled release behavior of drugs from the fibers comprising the biodegradable copolymer of polycaprolactone (PCL) and poly(ethylphosphate) (PCLEEP) was also investigated. The copolymers were synthesized through ring-opening polymerization of caprolactone and ethyl ethylene phosphate (EEP). The results show that delicate compounds such as proteins can better retain their bioactivity in encapsulation process involving PEC.",

author = "Leong, \{K. W.\} and Liao, \{I. C.\} and E. Yim and S. Lim and A. Wan and J. Wen and Chew, \{S. Y.\} and Chua, \{K. N.\} and S. Ramakrishna and Mao, \{H. Q.\}",

year = "2004",

language = "English",

isbn = "1877040193",

series = "Transactions - 7th World Biomaterials Congress",

pages = "189",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

}

TY - GEN

T1 - Controlled release systems designed for regenerative medicine

AU - Leong, K. W.

AU - Liao, I. C.

AU - Yim, E.

AU - Lim, S.

AU - Wan, A.

AU - Wen, J.

AU - Chew, S. Y.

AU - Chua, K. N.

AU - Ramakrishna, S.

AU - Mao, H. Q.

PY - 2004

Y1 - 2004

N2 - The features of two fibrous controlled release systems where the drug-loaded fibers are fabricated by electrospinning and polyelectrolyte complexation (PEC) were investigated. The controlled release behavior of drugs from the fibers comprising the biodegradable copolymer of polycaprolactone (PCL) and poly(ethylphosphate) (PCLEEP) was also investigated. The copolymers were synthesized through ring-opening polymerization of caprolactone and ethyl ethylene phosphate (EEP). The results show that delicate compounds such as proteins can better retain their bioactivity in encapsulation process involving PEC.

AB - The features of two fibrous controlled release systems where the drug-loaded fibers are fabricated by electrospinning and polyelectrolyte complexation (PEC) were investigated. The controlled release behavior of drugs from the fibers comprising the biodegradable copolymer of polycaprolactone (PCL) and poly(ethylphosphate) (PCLEEP) was also investigated. The copolymers were synthesized through ring-opening polymerization of caprolactone and ethyl ethylene phosphate (EEP). The results show that delicate compounds such as proteins can better retain their bioactivity in encapsulation process involving PEC.

UR - http://www.scopus.com/inward/record.url?scp=13844297427&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844297427&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:13844297427

SN - 1877040193

SN - 9781877040191

T3 - Transactions - 7th World Biomaterials Congress

SP - 189

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -

Controlled release systems designed for regenerative medicine

Abstract

Publication series

Conference

ASJC Scopus Subject Areas

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