Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

Chao Feng; Teck Peng Loh

doi:10.1039/c2sc21164e

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

Chao Feng, Teck Peng Loh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

249 Citations (Scopus)

Abstract

Copper-catalyzed olefinic trifluoromethylation and oxytrifluoromethylation of enamides is reported. The direct olefinic C-H trifluoromethylation constitutes an efficient method for the stereoselective synthesis of β-trifluoromethyl substituted enamides.

Original language	English
Pages (from-to)	3458-3462
Number of pages	5
Journal	Chemical Science
Volume	3
Issue number	12
DOIs	https://doi.org/10.1039/c2sc21164e
Publication status	Published - Dec 2012
Externally published	Yes

ASJC Scopus Subject Areas

General Chemistry

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10.1039/c2sc21164e

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title = "Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature",

abstract = "Copper-catalyzed olefinic trifluoromethylation and oxytrifluoromethylation of enamides is reported. The direct olefinic C-H trifluoromethylation constitutes an efficient method for the stereoselective synthesis of β-trifluoromethyl substituted enamides.",

author = "Chao Feng and Loh, {Teck Peng}",

year = "2012",

month = dec,

doi = "10.1039/c2sc21164e",

language = "English",

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pages = "3458--3462",

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issn = "2041-6520",

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AU - Feng, Chao

AU - Loh, Teck Peng

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AB - Copper-catalyzed olefinic trifluoromethylation and oxytrifluoromethylation of enamides is reported. The direct olefinic C-H trifluoromethylation constitutes an efficient method for the stereoselective synthesis of β-trifluoromethyl substituted enamides.

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EP - 3462

JO - Chemical Science

JF - Chemical Science

IS - 12

ER -

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

Abstract

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