[Cp∗IrCl2]2-catalysed cyclization of 2-alkynylanilines into indoles

Elumalai Kumaran; Weng Kee Leong

doi:10.1016/j.tetlet.2014.08.053

[Cp∗IrCl₂]₂-catalysed cyclization of 2-alkynylanilines into indoles

Elumalai Kumaran, Weng Kee Leong^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

[Cp∗IrCl₂]₂ catalyses the cyclization of 2-alkynylanilines into indoles. A wide variety of substrates is tolerated. A reaction pathway involving intramolecular hydroamination is proposed.

Original language	English
Pages (from-to)	5495-5498
Number of pages	4
Journal	Tetrahedron Letters
Volume	55
Issue number	40
DOIs	https://doi.org/10.1016/j.tetlet.2014.08.053
Publication status	Published - Oct 1 2014
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Ltd. All rights reserved.

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

2-Alkynylaniline
Catalytic hydroamination
Indole
Iridium

Access to Document

10.1016/j.tetlet.2014.08.053

Cite this

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title = "[Cp∗IrCl2]2-catalysed cyclization of 2-alkynylanilines into indoles",

abstract = "[Cp∗IrCl2]2 catalyses the cyclization of 2-alkynylanilines into indoles. A wide variety of substrates is tolerated. A reaction pathway involving intramolecular hydroamination is proposed.",

keywords = "2-Alkynylaniline, Catalytic hydroamination, Indole, Iridium",

author = "Elumalai Kumaran and Leong, {Weng Kee}",

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AU - Leong, Weng Kee

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