Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis

C. Yoon Kim; Jin Kim; Juha Song; Hanseul Oh; Jae Hak Park

doi:10.1016/j.dib.2016.01.021

Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis

C. Yoon Kim, Jin Kim, Juha Song, Hanseul Oh, Jae Hak Park^*

^*Corresponding author for this work

Seoul National University

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].

Original language	English
Pages (from-to)	706-709
Number of pages	4
Journal	Data in Brief
Volume	6
DOIs	https://doi.org/10.1016/j.dib.2016.01.021
Publication status	Published - Mar 1 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016 The Authors.

ASJC Scopus Subject Areas

General

Keywords

Neurotoxicity
Trimethyltin chloride
Zebrafish

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10.1016/j.dib.2016.01.021

Cite this

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title = "Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis",

abstract = "Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].",

keywords = "Neurotoxicity, Trimethyltin chloride, Zebrafish",

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doi = "10.1016/j.dib.2016.01.021",

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T1 - Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis

AU - Kim, C. Yoon

AU - Kim, Jin

AU - Song, Juha

AU - Oh, Hanseul

AU - Park, Jae Hak

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].

AB - Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].

KW - Neurotoxicity

KW - Trimethyltin chloride

KW - Zebrafish

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DO - 10.1016/j.dib.2016.01.021

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JO - Data in Brief

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ER -

Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

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