De immunochemische fecaaloccultbloedtest in een screeningsstudie naar colorectaal carcinoom

A. J. Van Vuuren; A. H.C. Van Roon; F. M. Verheijen; J. Francke; E. J. Kuipers; J. G. Boonstra

De immunochemische fecaaloccultbloedtest in een screeningsstudie naar colorectaal carcinoom

Translated title of the contribution: Immunochemical fecal occult blood test in a screening program for colorectal cancer

A. J. Van Vuuren, A. H.C. Van Roon, F. M. Verheijen, J. Francke, E. J. Kuipers, J. G. Boonstra

Research output: Contribution to journal › Article › peer-review

Abstract

The Health Council of the Netherlands advised on a national screening program for colorectal cancer (CRC) in November last year. Studies have already shown that screening for CRC using the guaiac based fecal occult blood test (gFOBT) reduces mortality, and more recently, results have been published using the immunological FOBT (iFOBT). The gFOBT and iFOBT do not differ in their CRC-detection rate, however, more advanced adenomas are found using the iFOBT. While the iFOBT is a quantitative test, it offers the possibility of choosing different cut-off points. It appears that, both clinical and analytical, a cut-off point of 75 ng/ml can be used, if adequate capacity for colonoscopy is available.

Translated title of the contribution	Immunochemical fecal occult blood test in a screening program for colorectal cancer
Original language	Dutch (Belgium)
Pages (from-to)	27-30
Number of pages	4
Journal	Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde
Volume	35
Issue number	1
Publication status	Published - Jan 2010
Externally published	Yes

ASJC Scopus Subject Areas

Clinical Biochemistry
Biochemistry, medical

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "De immunochemische fecaaloccultbloedtest in een screeningsstudie naar colorectaal carcinoom",

abstract = "The Health Council of the Netherlands advised on a national screening program for colorectal cancer (CRC) in November last year. Studies have already shown that screening for CRC using the guaiac based fecal occult blood test (gFOBT) reduces mortality, and more recently, results have been published using the immunological FOBT (iFOBT). The gFOBT and iFOBT do not differ in their CRC-detection rate, however, more advanced adenomas are found using the iFOBT. While the iFOBT is a quantitative test, it offers the possibility of choosing different cut-off points. It appears that, both clinical and analytical, a cut-off point of 75 ng/ml can be used, if adequate capacity for colonoscopy is available.",

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AU - Van Vuuren, A. J.

AU - Van Roon, A. H.C.

AU - Verheijen, F. M.

AU - Francke, J.

AU - Kuipers, E. J.

AU - Boonstra, J. G.

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N2 - The Health Council of the Netherlands advised on a national screening program for colorectal cancer (CRC) in November last year. Studies have already shown that screening for CRC using the guaiac based fecal occult blood test (gFOBT) reduces mortality, and more recently, results have been published using the immunological FOBT (iFOBT). The gFOBT and iFOBT do not differ in their CRC-detection rate, however, more advanced adenomas are found using the iFOBT. While the iFOBT is a quantitative test, it offers the possibility of choosing different cut-off points. It appears that, both clinical and analytical, a cut-off point of 75 ng/ml can be used, if adequate capacity for colonoscopy is available.

AB - The Health Council of the Netherlands advised on a national screening program for colorectal cancer (CRC) in November last year. Studies have already shown that screening for CRC using the guaiac based fecal occult blood test (gFOBT) reduces mortality, and more recently, results have been published using the immunological FOBT (iFOBT). The gFOBT and iFOBT do not differ in their CRC-detection rate, however, more advanced adenomas are found using the iFOBT. While the iFOBT is a quantitative test, it offers the possibility of choosing different cut-off points. It appears that, both clinical and analytical, a cut-off point of 75 ng/ml can be used, if adequate capacity for colonoscopy is available.

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De immunochemische fecaaloccultbloedtest in een screeningsstudie naar colorectaal carcinoom

Abstract

ASJC Scopus Subject Areas

UN SDGs

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