Detecting metabolic activities of bacteria using a simple carbon nanotube device for high-throughput screening of anti-bacterial drugs

Yinxi Huang, Herry Gunadi Sudibya, Peng Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

In this contribution, we demonstrate a simple carbon nanotube device to electrically detect the presence of bacteria (Escherichai coli) with high sensitivity (<100. cfu/mL) and the glucose triggered metabolic activities of bacteria in real-time. As proof-of-concept demonstration, we also show that this nanoelectronic approach can be employed for high-throughput screening of anti-bacterial drugs.

Original languageEnglish
Pages (from-to)4257-4261
Number of pages5
JournalBiosensors and Bioelectronics
Volume26
Issue number10
DOIs
Publication statusPublished - Jun 15 2011
Externally publishedYes

ASJC Scopus Subject Areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

Keywords

  • Bacteria
  • Carbon nanotube
  • Drug screening
  • Nanoelectronic biosensors

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