Detection of Bacteria in Water with β-Galactosidase-Coated Magnetic Nanoparticles

Mingyue Cui, Hao Chang, Yang Zhong, Min Wang, Tianze Wu, Xiao Hu, Zhichuan J. Xu, Chenjie Xu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Pathogenic contamination and resistant bacterial infections remain critical concerns in both developed and developing countries. Rapid and sensitive detection of pathogens is still a key requirement for both environmental and clinical settings. This article introduces a simple, colorimetric, cost-effective, and high-throughput system based on a positively charged iron oxide/enzyme complex for the detection of both gram-positive and gram-negative bacteria in water between 103 and 108 cfu/mL. This study provides an effective strategy for the identification and purification of pathogen contamination in drinking water.

Original languageEnglish
Pages (from-to)624-630
Number of pages7
JournalSLAS Technology
Volume23
Issue number6
DOIs
Publication statusPublished - Dec 1 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018 Society for Laboratory Automation and Screening.

ASJC Scopus Subject Areas

  • General Medicine

Keywords

  • bacterial detection
  • colorimetric assay
  • magnetic nanoparticles

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