Diagnosing COVID-19: The Disease and Tools for Detection

Buddhisha Udugama; Pranav Kadhiresan; Hannah N. Kozlowski; Ayden Malekjahani; Matthew Osborne; Vanessa Y.C. Li; Hongmin Chen; Samira Mubareka; Jonathan B. Gubbay; Warren C.W. Chan

doi:10.1021/acsnano.0c02624

Diagnosing COVID-19: The Disease and Tools for Detection

Buddhisha Udugama, Pranav Kadhiresan, Hannah N. Kozlowski, Ayden Malekjahani, Matthew Osborne, Vanessa Y.C. Li, Hongmin Chen, Samira Mubareka, Jonathan B. Gubbay, Warren C.W. Chan^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

1380 Citations (Scopus)

Abstract

COVID-19 has spread globally since its discovery in Hubei province, China in December 2019. A combination of computed tomography imaging, whole genome sequencing, and electron microscopy were initially used to screen and identify SARS-CoV-2, the viral etiology of COVID-19. The aim of this review article is to inform the audience of diagnostic and surveillance technologies for SARS-CoV-2 and their performance characteristics. We describe point-of-care diagnostics that are on the horizon and encourage academics to advance their technologies beyond conception. Developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak would be useful in preventing future epidemics.

Original language	English
Pages (from-to)	3822-3835
Number of pages	14
Journal	ACS Nano
Volume	14
Issue number	4
DOIs	https://doi.org/10.1021/acsnano.0c02624
Publication status	Published - Apr 28 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020 American Chemical Society.

ASJC Scopus Subject Areas

General Materials Science
General Engineering
General Physics and Astronomy

Keywords

COVID-19
diagnostics
pandemic
PCR
SARS-CoV-2
surveillance

Access to Document

10.1021/acsnano.0c02624

Cite this

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title = "Diagnosing COVID-19: The Disease and Tools for Detection",

abstract = "COVID-19 has spread globally since its discovery in Hubei province, China in December 2019. A combination of computed tomography imaging, whole genome sequencing, and electron microscopy were initially used to screen and identify SARS-CoV-2, the viral etiology of COVID-19. The aim of this review article is to inform the audience of diagnostic and surveillance technologies for SARS-CoV-2 and their performance characteristics. We describe point-of-care diagnostics that are on the horizon and encourage academics to advance their technologies beyond conception. Developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak would be useful in preventing future epidemics.",

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AU - Kadhiresan, Pranav

AU - Kozlowski, Hannah N.

AU - Malekjahani, Ayden

AU - Osborne, Matthew

AU - Li, Vanessa Y.C.

AU - Chen, Hongmin

AU - Mubareka, Samira

AU - Gubbay, Jonathan B.

AU - Chan, Warren C.W.

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Diagnosing COVID-19: The Disease and Tools for Detection

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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