Abstract
Extracellular vesicles (EVs) are small membrane-bound vehicles which has been gaining traction in the recent years for their diagnostic and therapeutic values. Depending on their biogenesis, they are termed as exosomes (endosomal) or microvesicles (plasma membrane), carrying with them a myriad of cargo (lipids, nucleic acids and proteins) from their host cells. Despite being a promising biomarker, EVs are arduous to isolate due to their size (~50nm - 1µm). In this work, we describe a high-throughput and label-free spiral microdevice for EVs isolation directly from whole blood.
| Original language | English |
|---|---|
| Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 4-5 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419000 |
| Publication status | Published - 2019 |
| Externally published | Yes |
| Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: Oct 27 2019 → Oct 31 2019 |
Publication series
| Name | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
|---|
Conference
| Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
|---|---|
| Country/Territory | Switzerland |
| City | Basel |
| Period | 10/27/19 → 10/31/19 |
Bibliographical note
Publisher Copyright:© 2019 CBMS-0001.
ASJC Scopus Subject Areas
- Bioengineering
- Chemical Engineering (miscellaneous)
Keywords
- Blood
- Exosomes
- Extracellular Vesicles
- Inertial Microfluidics
- Microvesicles