Direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres

Poernomo Gunawan; Rong Xu

doi:10.1021/cm803203x

Direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres

Poernomo Gunawan, Rong Xu^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

125 Citations (Scopus)

Abstract

The direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres was studied. The precursor Mg₂Al-LDH nanocrystals (LDH-NCs) were synthesized using a similar method from the solution of Mg(NO₃)₂ and Al(NO₃)₂ in the presence of NaOH in pure methanol. The XRD pattern of LDH-NCs indicates the formation of LDH structure with a rhombohedral symmetry, estimating the thickness of LDH-NCs based on the fwhm of the basal plane is 10 nm. the carbon nanospheres (CNS) prepared, is reported to have a negative zeta potential of -13.4 mV due to its abundant surface hydroxyl groups. The reconstruction of the resultant oxide product to LDHs intercalated with drug anions performed in ethylene glycol with a controlled amount of water.

Original language	English
Pages (from-to)	781-783
Number of pages	3
Journal	Chemistry of Materials
Volume	21
Issue number	5
DOIs	https://doi.org/10.1021/cm803203x
Publication status	Published - Mar 10 2009
Externally published	Yes

ASJC Scopus Subject Areas

General Chemistry
General Chemical Engineering
Materials Chemistry

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title = "Direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres",

abstract = "The direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres was studied. The precursor Mg2Al-LDH nanocrystals (LDH-NCs) were synthesized using a similar method from the solution of Mg(NO3)2 and Al(NO3)2 in the presence of NaOH in pure methanol. The XRD pattern of LDH-NCs indicates the formation of LDH structure with a rhombohedral symmetry, estimating the thickness of LDH-NCs based on the fwhm of the basal plane is 10 nm. the carbon nanospheres (CNS) prepared, is reported to have a negative zeta potential of -13.4 mV due to its abundant surface hydroxyl groups. The reconstruction of the resultant oxide product to LDHs intercalated with drug anions performed in ethylene glycol with a controlled amount of water.",

author = "Poernomo Gunawan and Rong Xu",

year = "2009",

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doi = "10.1021/cm803203x",

language = "English",

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journal = "Chemistry of Materials",

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publisher = "American Chemical Society",

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T1 - Direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres

AU - Gunawan, Poernomo

AU - Xu, Rong

PY - 2009/3/10

Y1 - 2009/3/10

N2 - The direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres was studied. The precursor Mg2Al-LDH nanocrystals (LDH-NCs) were synthesized using a similar method from the solution of Mg(NO3)2 and Al(NO3)2 in the presence of NaOH in pure methanol. The XRD pattern of LDH-NCs indicates the formation of LDH structure with a rhombohedral symmetry, estimating the thickness of LDH-NCs based on the fwhm of the basal plane is 10 nm. the carbon nanospheres (CNS) prepared, is reported to have a negative zeta potential of -13.4 mV due to its abundant surface hydroxyl groups. The reconstruction of the resultant oxide product to LDHs intercalated with drug anions performed in ethylene glycol with a controlled amount of water.

AB - The direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres was studied. The precursor Mg2Al-LDH nanocrystals (LDH-NCs) were synthesized using a similar method from the solution of Mg(NO3)2 and Al(NO3)2 in the presence of NaOH in pure methanol. The XRD pattern of LDH-NCs indicates the formation of LDH structure with a rhombohedral symmetry, estimating the thickness of LDH-NCs based on the fwhm of the basal plane is 10 nm. the carbon nanospheres (CNS) prepared, is reported to have a negative zeta potential of -13.4 mV due to its abundant surface hydroxyl groups. The reconstruction of the resultant oxide product to LDHs intercalated with drug anions performed in ethylene glycol with a controlled amount of water.

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Direct assembly of anisotropic layered double hydroxide (LDH) nanocrystals on spherical template for fabrication of drug-LDH hollow nanospheres

Abstract

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