Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis

Guillaume Perry; Florian Lapierre; Yannick Coffinier; Vincent Thomy; Rabah Boukherroub; Congxiang Lu; Siu Hon Tsang; Beng Kang Tay; Philippe Coquet

doi:10.1109/INEC.2013.6466051

Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis

Guillaume Perry^*, Florian Lapierre, Yannick Coffinier, Vincent Thomy, Rabah Boukherroub, Congxiang Lu, Siu Hon Tsang, Beng Kang Tay, Philippe Coquet

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

We present in this paper a microsystem coupling electrowetting on digital microfluidic and nanostructured surfaces for matrix-free Laser Desorption/Ionization Mass Spectrometry (LDI-MS) analysis of small biomolecules. Silicon nanowires are processed to form highly sensitive pads for LDI analysis and also to produce superhydrophobic surfaces for enhanced transfer of droplets containing the analytes to the analyzing pads. By this way, analysis of low molecular weight compounds with high sensitivity can be achieved. In addition, wetting properties of carbon nanotubes surfaces are investigated in the perspective of further increasing the detection performances.

Original language	English
Title of host publication	Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013
Pages	374-377
Number of pages	4
DOIs	https://doi.org/10.1109/INEC.2013.6466051
Publication status	Published - 2013
Externally published	Yes
Event	2013 IEEE 5th International Nanoelectronics Conference, INEC 2013 - Singapore, Singapore Duration: Jan 2 2013 → Jan 4 2013

Publication series

Name	Proceedings - Winter Simulation Conference
ISSN (Print)	0891-7736

Conference

Conference	2013 IEEE 5th International Nanoelectronics Conference, INEC 2013
Country/Territory	Singapore
City	Singapore
Period	1/2/13 → 1/4/13

ASJC Scopus Subject Areas

Software
Modelling and Simulation
Computer Science Applications

Keywords

Carbon Nanotubes
EWOD
Mass Spectrometry Analysis
Silicon Nanowires
Superhydrophobic Surfaces

Access to Document

10.1109/INEC.2013.6466051

Cite this

Perry, G., Lapierre, F., Coffinier, Y., Thomy, V., Boukherroub, R., Lu, C., Tsang, S. H., Tay, B. K., & Coquet, P. (2013). Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis. In Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013 (pp. 374-377). Article 6466051 (Proceedings - Winter Simulation Conference). https://doi.org/10.1109/INEC.2013.6466051

@inproceedings{e7687af3554c4bf0b7c7881a0e39cba8,

title = "Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis",

abstract = "We present in this paper a microsystem coupling electrowetting on digital microfluidic and nanostructured surfaces for matrix-free Laser Desorption/Ionization Mass Spectrometry (LDI-MS) analysis of small biomolecules. Silicon nanowires are processed to form highly sensitive pads for LDI analysis and also to produce superhydrophobic surfaces for enhanced transfer of droplets containing the analytes to the analyzing pads. By this way, analysis of low molecular weight compounds with high sensitivity can be achieved. In addition, wetting properties of carbon nanotubes surfaces are investigated in the perspective of further increasing the detection performances.",

keywords = "Carbon Nanotubes, EWOD, Mass Spectrometry Analysis, Silicon Nanowires, Superhydrophobic Surfaces",

author = "Guillaume Perry and Florian Lapierre and Yannick Coffinier and Vincent Thomy and Rabah Boukherroub and Congxiang Lu and Tsang, {Siu Hon} and Tay, {Beng Kang} and Philippe Coquet",

year = "2013",

doi = "10.1109/INEC.2013.6466051",

language = "English",

isbn = "9781467348416",

series = "Proceedings - Winter Simulation Conference",

pages = "374--377",

booktitle = "Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013",

note = "2013 IEEE 5th International Nanoelectronics Conference, INEC 2013 ; Conference date: 02-01-2013 Through 04-01-2013",

}

Perry, G, Lapierre, F, Coffinier, Y, Thomy, V, Boukherroub, R, Lu, C, Tsang, SH, Tay, BK & Coquet, P 2013, Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis. in Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013., 6466051, Proceedings - Winter Simulation Conference, pp. 374-377, 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013, Singapore, Singapore, 1/2/13. https://doi.org/10.1109/INEC.2013.6466051

Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis. / Perry, Guillaume; Lapierre, Florian; Coffinier, Yannick et al.
Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013. 2013. p. 374-377 6466051 (Proceedings - Winter Simulation Conference).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis

AU - Perry, Guillaume

AU - Lapierre, Florian

AU - Coffinier, Yannick

AU - Thomy, Vincent

AU - Boukherroub, Rabah

AU - Lu, Congxiang

AU - Tsang, Siu Hon

AU - Tay, Beng Kang

AU - Coquet, Philippe

PY - 2013

Y1 - 2013

N2 - We present in this paper a microsystem coupling electrowetting on digital microfluidic and nanostructured surfaces for matrix-free Laser Desorption/Ionization Mass Spectrometry (LDI-MS) analysis of small biomolecules. Silicon nanowires are processed to form highly sensitive pads for LDI analysis and also to produce superhydrophobic surfaces for enhanced transfer of droplets containing the analytes to the analyzing pads. By this way, analysis of low molecular weight compounds with high sensitivity can be achieved. In addition, wetting properties of carbon nanotubes surfaces are investigated in the perspective of further increasing the detection performances.

AB - We present in this paper a microsystem coupling electrowetting on digital microfluidic and nanostructured surfaces for matrix-free Laser Desorption/Ionization Mass Spectrometry (LDI-MS) analysis of small biomolecules. Silicon nanowires are processed to form highly sensitive pads for LDI analysis and also to produce superhydrophobic surfaces for enhanced transfer of droplets containing the analytes to the analyzing pads. By this way, analysis of low molecular weight compounds with high sensitivity can be achieved. In addition, wetting properties of carbon nanotubes surfaces are investigated in the perspective of further increasing the detection performances.

KW - Carbon Nanotubes

KW - EWOD

KW - Mass Spectrometry Analysis

KW - Silicon Nanowires

KW - Superhydrophobic Surfaces

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DO - 10.1109/INEC.2013.6466051

M3 - Conference contribution

AN - SCOPUS:84874765352

SN - 9781467348416

T3 - Proceedings - Winter Simulation Conference

SP - 374

EP - 377

BT - Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013

T2 - 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013

Y2 - 2 January 2013 through 4 January 2013

ER -

Perry G, Lapierre F, Coffinier Y, Thomy V, Boukherroub R, Lu C et al. Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis. In Proceedings of the 2013 IEEE 5th International Nanoelectronics Conference, INEC 2013. 2013. p. 374-377. 6466051. (Proceedings - Winter Simulation Conference). doi: 10.1109/INEC.2013.6466051

Droplet based lab-on-chip microfluidic Microsystems integrated nanostructured surfaces for high sensitive mass spectrometry analysis

Abstract

Publication series

Conference

ASJC Scopus Subject Areas

Keywords

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