Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids

Shun Jun Ji; Min Feng Zhou; Da Gong Gu; Shun Yi Wang; Teck Peng Loh

doi:10.1055/s-2003-41464

Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids

Shun Jun Ji^*, Min Feng Zhou, Da Gong Gu, Shun Yi Wang, Teck Peng Loh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

148 Citations (Scopus)

Abstract

Efficient electrophilic substitution reactions of indoles with various aldehydes proceed smoothly in ionic liquids using Lewis acids, In(OTf) ₃, YbCl₃, InCl₃, BiCl₃, and ZnCl₂, to afford the corresponding bis(indolyl)methanes in high yields.

Original language	English
Pages (from-to)	2077-2079
Number of pages	3
Journal	Synlett
Issue number	13
DOIs	https://doi.org/10.1055/s-2003-41464
Publication status	Published - 2003
Externally published	Yes

ASJC Scopus Subject Areas

Organic Chemistry

Keywords

Bis(indolyl)methanes
In(OTf)
Indoles
Ionic liquids
Lewis acids

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title = "Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids",

abstract = "Efficient electrophilic substitution reactions of indoles with various aldehydes proceed smoothly in ionic liquids using Lewis acids, In(OTf) 3, YbCl3, InCl3, BiCl3, and ZnCl2, to afford the corresponding bis(indolyl)methanes in high yields.",

keywords = "Bis(indolyl)methanes, In(OTf), Indoles, Ionic liquids, Lewis acids",

author = "Ji, {Shun Jun} and Zhou, {Min Feng} and Gu, {Da Gong} and Wang, {Shun Yi} and Loh, {Teck Peng}",

year = "2003",

doi = "10.1055/s-2003-41464",

language = "English",

pages = "2077--2079",

journal = "Synlett",

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T1 - Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids

AU - Ji, Shun Jun

AU - Zhou, Min Feng

AU - Gu, Da Gong

AU - Wang, Shun Yi

AU - Loh, Teck Peng

PY - 2003

Y1 - 2003

N2 - Efficient electrophilic substitution reactions of indoles with various aldehydes proceed smoothly in ionic liquids using Lewis acids, In(OTf) 3, YbCl3, InCl3, BiCl3, and ZnCl2, to afford the corresponding bis(indolyl)methanes in high yields.

AB - Efficient electrophilic substitution reactions of indoles with various aldehydes proceed smoothly in ionic liquids using Lewis acids, In(OTf) 3, YbCl3, InCl3, BiCl3, and ZnCl2, to afford the corresponding bis(indolyl)methanes in high yields.

KW - Bis(indolyl)methanes

KW - In(OTf)

KW - Indoles

KW - Ionic liquids

KW - Lewis acids

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U2 - 10.1055/s-2003-41464

DO - 10.1055/s-2003-41464

M3 - Article

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SP - 2077

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JO - Synlett

JF - Synlett

IS - 13

ER -

Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids

Abstract

ASJC Scopus Subject Areas

Keywords

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