Enantioselective Cationic Polyene Cyclization vs Enantioselective Intramolecular Carbonyl-Ene Reaction

Yu Jun Zhao; Bin Li; Li Jun Serena Tan; Zhi Liang Shen; Teck Peng Loh

doi:10.1021/ja104119j

Enantioselective Cationic Polyene Cyclization vs Enantioselective Intramolecular Carbonyl-Ene Reaction

Yu Jun Zhao, Bin Li, Li Jun Serena Tan, Zhi Liang Shen, Teck Peng Loh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Abstract

This paper describes highly efficient catalytic enantioselective cationic polyene cyclization and catalytic enantioselective intramolecular carbonyl-ene reaction in good to high yields with high enantioselectivities. The intimate relationship and mechanistic differences between the two enantioselective reactions were studied in detail. In addition, the cyclization products are versatile and useful building blocks for natural products and pharmaceuticals syntheses.

Original language	English
Pages (from-to)	10242-10244
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	132
Issue number	30
DOIs	https://doi.org/10.1021/ja104119j
Publication status	Published - Aug 4 2010
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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abstract = "This paper describes highly efficient catalytic enantioselective cationic polyene cyclization and catalytic enantioselective intramolecular carbonyl-ene reaction in good to high yields with high enantioselectivities. The intimate relationship and mechanistic differences between the two enantioselective reactions were studied in detail. In addition, the cyclization products are versatile and useful building blocks for natural products and pharmaceuticals syntheses.",

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AU - Shen, Zhi Liang

AU - Loh, Teck Peng

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N2 - This paper describes highly efficient catalytic enantioselective cationic polyene cyclization and catalytic enantioselective intramolecular carbonyl-ene reaction in good to high yields with high enantioselectivities. The intimate relationship and mechanistic differences between the two enantioselective reactions were studied in detail. In addition, the cyclization products are versatile and useful building blocks for natural products and pharmaceuticals syntheses.

AB - This paper describes highly efficient catalytic enantioselective cationic polyene cyclization and catalytic enantioselective intramolecular carbonyl-ene reaction in good to high yields with high enantioselectivities. The intimate relationship and mechanistic differences between the two enantioselective reactions were studied in detail. In addition, the cyclization products are versatile and useful building blocks for natural products and pharmaceuticals syntheses.

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Enantioselective Cationic Polyene Cyclization vs Enantioselective Intramolecular Carbonyl-Ene Reaction

Abstract

ASJC Scopus Subject Areas

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