Exploring primary liver macrophages for studying quantum dot interactions with biological systems

Hans C. Fischer; Tanya S. Hauck; Alejandro Gómez-Aristizábal; Warren C.W. Chan

doi:10.1002/adma.200904231

Exploring primary liver macrophages for studying quantum dot interactions with biological systems

Hans C. Fischer, Tanya S. Hauck, Alejandro Gómez-Aristizábal, Warren C.W. Chan

University of Toronto

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

(Figure Presented) The effect quantum dots have on primary rat macrophages is investigated, and the findings are compared to in vivo data. In vitro uptake kinetics and degradation both reflect in vivo findings; therefore, primary macrophages are shown to be an appropriate system with which to investigate cellular responses to quantum dots and other nanoparticles in order to guide in vivo studies.

Original language	English
Pages (from-to)	2520-2524
Number of pages	5
Journal	Advanced Materials
Volume	22
Issue number	23
DOIs	https://doi.org/10.1002/adma.200904231
Publication status	Published - Jun 18 2010
Externally published	Yes

ASJC Scopus Subject Areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.200904231

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AU - Hauck, Tanya S.

AU - Gómez-Aristizábal, Alejandro

AU - Chan, Warren C.W.

PY - 2010/6/18

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AB - (Figure Presented) The effect quantum dots have on primary rat macrophages is investigated, and the findings are compared to in vivo data. In vitro uptake kinetics and degradation both reflect in vivo findings; therefore, primary macrophages are shown to be an appropriate system with which to investigate cellular responses to quantum dots and other nanoparticles in order to guide in vivo studies.

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Exploring primary liver macrophages for studying quantum dot interactions with biological systems

Abstract

ASJC Scopus Subject Areas

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